Proteasome-mediated effects on amyloid precursor protein processing at the γ-secretase site

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Proteasome-mediated effects on amyloid precursor protein processing at the γ -secretase site

Fiona FLOOD*, Suzanne MURPHY†, Richard F. COWBURN*, Lars LANNFELT‡, Brian WALKER§ and Janet A. JOHNSTON†1 *Karolinska Institute, Neurotec Department, Division of Experimental Geriatrics, Huddinge, S-14186, Sweden, †Queen’s University, Belfast, School of Biology and Biochemistry, Medical Biology Centre, 97 Lisburn Road, Belfast BT9 7BL, Northern Ireland, U.K., ‡Uppsala University Hospital, Depar...

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The discrepancy between presenilin subcellular localization and γ-secretase processing of amyloid precursor protein

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ژورنال

عنوان ژورنال: Biochemical Journal

سال: 2005

ISSN: 0264-6021,1470-8728

DOI: 10.1042/bj20041145